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Authors’ response
*For correspondence: drlaway@gmail.com
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Received: ,
Accepted: ,
Sir,
We greatly appreciate the reader’s interest in our article1 published in the June 2024 issue of Indian Journal of Medical Research, which has raised intriguing questions.
As rightly pointed by the author that the aforementioned study has a small sample size, and its conclusions may not be generalizable2. This represented our attempt to study pituitary functions within this cohort of patients, and we hope that larger studies will be conducted in the future.
Regarding confounding factors, we excluded all chronic diseases and conditions, including drug intake that could have interfered with the assessment of pituitary hormones. Furthermore, the patients were monitored and reassessed, which plausibly minimized the impact of acute stress on pituitary hormones.
As mentioned in the introduction of the article, we hypothesized that hypoperfusion due to a complete heart block could lead to vasospasm and hypoxia of pituitary tissue, resulting in long-term pituitary dysfunction3.
We once again thank the reader for their insightful comments and the opportunity to elaborate on our study.
Financial support & sponsorship
None.
Conflicts of Interest
None.
Use of Artificial Intelligence (AI)-Assisted Technology for manuscript preparation
The authors confirm that there was no use of AI-assisted technology for assisting in the writing of the manuscript and no images were manipulated using AI.
References
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- Pituitary dysfunction in heart block: The need for broader insight. Indian J Med Res. 2025;161:428.
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- The central nervous system cytokine response to global ischemia following resuscitation from ventricular fibrillation in a porcine model. Resuscitation. 2009;80:249-52.
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