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OCT angiography in retinal and macular diseases
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This article was originally published by Medknow Publications & Media Pvt Ltd and was migrated to Scientific Scholar after the change of Publisher.
This book on OCT (optical coherence tomography) angiography is a comprehensive and timely publication. Unlike a typical atlas, this book describes the technology and its applications, the various available OCT angiography technologies and their respective limitations.
The book starts with a description of the available OCT angiography devices, and their technical specification. However, a comparative analysis of the same could have been useful for the readers to understand the advantages and disadvantages of each device.
An important chapter before the various pathologies, is on the OCT angiography in healthy subjects. This chapter demonstrates OCT angiography scans at various levels including choroid, importantly the different slabs to evaluate areas of interest. The chapters on age-related macular degeneration bring out interesting features of choroidal neovascular complexes including the changes during the anti- vascular endothelial growth factor (VEGF) therapy. Application of OCT angiography particularly in mixed neovascularization is demonstrated through interesting cases by Liang and Witkin in chapter 10.
Chapter 13 on OCT angiography findings of fibrosis in age-related macular degeneration greatly improves the understanding of various vascular patterns, however, the clinical applications of these patterns are yet to be explored. The chapters on vascular diseases such as diabetic retinopathy and vascular occlusion describe vascular changes in different layers and compare them with fluorescein angiography (FA). Chapter 23 compares OCT angiography with FA and concludes that the OCT angiography is non-inferior to FA in studying the posterior pole. This chapter demonstrates segmentation of vitreous to image neovascular complexes with good images. Sarraf D and colleagues in 2013 have demonstrated the inner nuclear layer ischemia using OCT angiography and have provided the evidence for paracentral acute middle maculopathy. The chapter on macular telangiectasia discusses the superiority of OCT angiography over other imaging techniques including FA and autofluorescence in this disease. Limited available information on OCT angiography in dystrophies is shared in a separate chapter, however, understanding on choroidal changes is still limited. The book ends with the chapters on paediatric and miscellaneous retinal diseases.
Overall, this book covers all aspects of this new technology from the basics to the clinical applications. It has many images on almost all clinically important conditions with a detailed legend and comparative images of FA, which allows better interpretation for clinicians to apply the same in their regular clinical practice.
Artifacts on OCT angiography is one of the biggest concerns at present. The authors of each chapter have brought out this topic very clearly, especially in its application in diseased eyes. However, a separate comprehensive chapter on artifacts with images could have improved the understanding for the readers.
This rapidly developing technology has seen many changes in recent past. However, this book forms the basic ground on understanding and development of OCT angiography technology for clinicians. This book is recommended for retina specialists, clinical researchers and fellows to learn about this upcoming technology, which eventually can become essential part of patient management.
