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Central retinal vein occlusion due to optic nerve invasion by metastasis from malignant peripheral nerve sheath tumour
*For correspondence: drvinod_agg@yahoo.com
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This article was originally published by Wolters Kluwer - Medknow and was migrated to Scientific Scholar after the change of Publisher.
A 52 yr old male† presented to the department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Science, New Delhi, India, in June 2019, with diminution of vision in his left eye for one month. Best-corrected visual acuity in the left eye was finger counting. The left eye revealed large peri-papillary choroidal metastasis (Figure A) that was confirmed on B scan ultrasound of the left eye (Figure B). The patient was on chemotherapy for local recurrence and widespread metastasis from malignant peripheral nerve sheath tumour on the chest wall, for which he underwent excision three years back. The histopathology report showed a low-grade spindle cell sarcoma (Figure C). The patient presented three months later with further diminution of vision in the left eye. Fundus examination revealed central retinal vein occlusion due to optic nerve infiltration by the metastasis (Figure D). Poor visual prognosis was explained to the patient and further follow up was advised in the department of oncology.
- (A) Clinical fundus photograph of the left eye showing peri-papillary choroidal mass suggestive of choroidal metastasis. (B) B scan ultrasound of the left eye showing choroidal mass involving the optic disc. (C) Histopathology of primary tumour (H and E stain, ×40) suggestive of spindle cell sarcoma. (D) Clinical fundus photograph of the left eye showing diffuse multiple haemorrhages, venous dilatation and tortuosity suggestive of central retinal vein occlusion along with peri-papillary choroidal mass (white arrow).
Conflicts of Interest: None.
